Polygenic associations with educational attainment

SBI contributors 

Prof. Dr. David Richter

Project description

This study used a DNA-based polygenic index to examine how genetic associations with educational attainment varied between East and West Germany around the time of reunification. Analyzing data from 1,930 individuals in the SOEP-G[ene] cohort, the researchers found no difference in genetic associations before reunification, but a significant increase in East Germany afterward. This suggests a gene–environment interaction, as the change was specific to education and not observed for a control trait like height. The findings support theories that genetic influences on education become more pronounced in contexts with greater social and educational opportunities. Replication in larger datasets is recommended. 

Status

Completed

Selected publications 

Fraemke, D., Willems, Y. E., Okbay, A., Lindenberger, U., Zinn, S., Wagner, G., Richter, D., Harden, K. P., Tucker-Drob, E. M., Hertwig, R., Koellinger, P., & Raffington, L. (2025). Polygenic associations with educational attainment in East versus West Germany: Differences emerge after reunification. Psychological Science. https://doi.org/10.1177/09567976251350965